Cytisine for 25 days
Cytisine is the active substance in Desmoxan, Tabex and Recigar. In these products, a tablet or capsule contains 1.5 mg of cytisine. It stimulates the same receptors in the brain as nicotine but more weakly, so it eases cravings, and a cigarette smoked during treatment gives less pleasure. One pack of Desmoxan contains 100 tablets and is enough for the whole course. For the first 3 days, the patient takes 6 tablets a day, in the last 5 days 1 or 2, and stops smoking by day 5 at the latest.
In an analysis of 4 studies involving 4,623 people, 30 percent more people taking cytisine than people given placebo were not smoking after at least six months. Most cytisine products are available without a prescription, and in September 2026 a pack for the whole course cost about PLN 40 to 78 in online pharmacies.
Nicotine patches for 8 to 12 weeks
A patch releases nicotine, which is absorbed through the skin. It does not deliver the tar or carbon monoxide found in smoke. How long treatment lasts depends on the manufacturer. The NiQuitin patch is worn for 24 hours at a time, at 21 mg for 6 weeks, and then at 14 mg and 7 mg for 2 weeks each. For people who smoke no more than 10 cigarettes a day, treatment starts at 14 mg and lasts 8 weeks, and the manufacturer does not recommend extending it. Nicorette Invisipatch is put on in the morning and taken off before bed. A strongly dependent person wears it at 25 mg for 8 weeks, and then at 15 mg and 10 mg for 2 weeks each, so treatment lasts 12 weeks.
In a summary of studies, patches increased the number of non-smokers by 64 percent compared with placebo or no treatment. However, a 2023 review found no clear evidence that wearing patches for longer increases the chance of quitting. Patches are sold without a prescription, and 10 weeks of treatment with 24-hour patches cost about PLN 606 to 930 in September 2026.
Gum, spray and lozenges for about 3 months
The patient uses Nicorette Classic Gum, Nicorette Spray and NiQuitin MINI lozenges whenever they feel like smoking, and the nicotine is absorbed through the lining of the mouth. Nicotine gum is used for at least 3 months and then gradually stopped. The spray is used at the full dose for 6 weeks, the number of doses is halved by the end of week 9, and in week 12 the patient uses no more than 4 doses a day. Lozenges are taken for 6 weeks and then less and less often, down to 1 or 2 a day.
Among people chewing gum, there were 49 percent more non-smokers than in comparison groups, and among people using lozenges 52 percent more. All these forms are available without a prescription. The patient paid PLN 78 to 100 for 105 pieces of 4 mg gum and PLN 62 to 85 for a spray with 150 doses.
Varenicline for 12 or 24 weeks
Varenicline, the active substance in Champix, in 0.5 and 1 mg tablets, acts on nicotinic receptors in a similar way to cytisine. The patient usually starts taking it 1 to 2 weeks before quitting. Treatment lasts 12 weeks. For someone who has stopped smoking during that time, the doctor may recommend another 12 weeks. In 2 studies involving 1,297 such people, continuing varenicline increased the number who did not go back to smoking by 23 percent. In 41 studies, varenicline more than doubled the number of non-smokers. It requires a prescription, but in September 2026 we did not find it in the pharmacies we checked.
Bupropion for at least 7 weeks
Bupropion, the active substance in Zyban, in 150 mg tablets, is an antidepressant that contains no nicotine. The patient starts taking it while still smoking, stops smoking within the first 2 weeks of treatment and takes the medicine for at least 7 weeks. In 45 studies, 64 percent more people were not smoking after treatment with bupropion than in placebo or no-treatment groups. The marketing authorisation for Zyban expired in December 2023.