Only partly, and not all to the same degree. A nicotine patch eases cravings that build up from a lack of nicotine, but in laboratory studies it did not suppress the sudden urge triggered by the sight of a cigarette. Nicotine gum reduced this urge after around a quarter of an hour. Data on the effectiveness of medicines come from a review of 319 studies published in 2023 by Cochrane, an independent scientific organisation that gathers the results of clinical trials and assesses how far they can be trusted. Prices are from September 2026.
The review assessed how well medicines worked by the proportion of people who were not smoking after at least six months. The differences shown compare treatment with placebo or no medicine.
When does a nicotine patch ease cravings, and when is it not enough?
In one experiment, 61 smokers went without smoking for 6 hours while wearing a patch with 21 mg of nicotine or a nicotine-free patch. Before and after this break, they were shown cigarettes and other objects. The nicotine patch reduced cravings and the low mood caused by the break from smoking itself, but the urge triggered by the sight of cigarettes rose just as much as in people wearing the nicotine-free patch.
A similar result came from a study of 158 people on their first day of quitting, who were randomly given a patch with 35 mg of nicotine, stronger than pharmacy patches, or a nicotine-free patch. The nicotine patch lowered the overall level of craving but did not limit the sudden rise in the urge after exposure to cigarettes. In people treated with nicotine, a stronger rise in this urge was linked with a higher chance of going back to smoking.
In Poland, the patches available are NiQuitin Przezroczysty, which releases nicotine around the clock, or Nicorette Invisipatch, worn for 16 hours and removed at night. A new patch is applied every day, and its strength is reduced gradually through the stages of treatment. Without other medicines, a patch helped about 2 more people per 100 treated to quit. A ten-week course of NiQuitin patches cost from PLN 606 to PLN 930 in pharmacies.
Which medicine helps with a sudden urge to smoke?
In a multicentre study, 296 people quit smoking with nicotine gum or nicotine-free gum. On the third day without cigarettes, they were exposed to a smoking-related cue in a research laboratory and then chewed their gum. At first, the urge fell in both groups, but after 15 minutes it fell clearly more in people chewing nicotine gum.
The forms used when a sudden urge strikes include Nicorette Classic Gum, NiQuitin MINI lozenges and Nicorette Spray mouth spray. Nicotine is absorbed from them through the lining of the mouth. The patient uses no more than 15 pieces of gum or 15 lozenges a day. With the spray, no more than 2 sprays can be used for one craving episode, 4 within an hour and 64 within 24 hours. For fast-acting forms of nicotine, the combined result was about 3 extra non-smokers per 100 compared with placebo or no medicine. The doctor can combine one of these forms of nicotine with a patch. Prices ranged from PLN 62 to PLN 85 for a 150-dose spray and from PLN 78 to PLN 100 for 105 pieces of 4 mg gum.
How do cytisine and varenicline affect the urge to smoke?
Cytisine, contained in Desmoxan, Tabex and Recigar tablets at 1.5 mg each, is a plant alkaloid that binds to the same brain receptors as nicotine but stimulates them more weakly. As a result, it eases withdrawal symptoms, and a cigarette smoked during treatment gives less pleasure. The number of tablets falls from 6 a day on days 1 to 3 down to 1 or 2 towards the end of the course, which lasts 25 days. Smoking must stop by day 5 of treatment. Cytisine helped about 7 more people per 100 to stop smoking, and a pack of 100 tablets for the whole course cost from PLN 40 to PLN 78. We found no study results on its effect on the urge triggered by the sight of a cigarette, only the description of a planned study using virtual reality.
Varenicline, the active substance in Champix, also stimulates nicotine receptors more weakly. In studies, it helped about 8 more people per 100 to quit. With bupropion, the active substance in Zyban, about 3 more people per 100 quit. In an experiment involving 40 smokers, varenicline reduced overall cravings and the urge triggered by the sight of a cigarette, but not when participants had been put under stress before seeing the cigarette. Both medicines are prescription-only. In December 2023, Zyban's marketing authorisation in Poland expired. When we looked for Champix in September 2026, none of the pharmacies we checked had it.
In studies, no medicine completely removed the urge triggered by surroundings, which is why the doctor chooses the medicine and the patient prepares with an addiction therapist for situations in which the urge returns.